发明名称 Solubility modulated drug delivery device
摘要 A solubility modulated drug delivery device for controlled release of a therapeutically active ingredient into an environment of use is disclosed. The device comprises a core composition of a solubility modulating agent consisting of a complexing agent or a surfactant and a diffusible, water soluble, therapeutically active agent. The core composition is surrounded by a water insoluble semipermeable wall which is substantially impermeable to the core composition and permeable to the fluids in the environment of use and contains apertures through which active agent is released.
申请公布号 US4994273(A) 申请公布日期 1991.02.19
申请号 US19890384116 申请日期 1989.07.20
申请人 MERCK & CO., INC. 发明人 ZENTNER, GAYLEN M.;MCCLELLAND, GREGORY A.
分类号 A61K9/00 主分类号 A61K9/00
代理机构 代理人
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