| 发明名称 |
CYCLIC TETRAPEPTIDE AND PRODUCTION THEREOF |
| 摘要 |
NEW MATERIAL:Compounds of RF-1023A (n=4) or RF-1023-B (n=3) represented by formula I (n is 4 or 3). EXAMPLE:A compound of formula II. USE:An anti-neoplastic agent. PREPARATION:A cyclic tetrapeptide-producing fungus [preferably Helicoma ambiens RF-1028 strain (FERM P-10680)] belonging to Helicoma genus is cultured in a culture medium. |
| 申请公布号 |
JPH0334991(A) |
申请公布日期 |
1991.02.14 |
| 申请号 |
JP19890170930 |
申请日期 |
1989.06.30 |
| 申请人 |
SHIONOGI & CO LTD |
发明人 |
SUGITA KENJI;ITAZAKI HIROSHI;MATSUMOTO KOICHI;KAWAMURA YOSHIMI |
| 分类号 |
A61K38/00;A61P35/00;C07K5/12;C07K14/37;C07K14/41;C12P21/04;C12R1/645 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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