| 摘要 |
Compounds of general formula I: …<IMAGE>… in which: … … - R1 denotes a hydrogen atom, a linear or branched alkyl radical containing from 1 to 6 carbon atoms, a linear or branched alkenyl radical containing from 2 to 6 carbon atoms, an arylalkyl radical of 7 to 10 carbon atoms capable of carrying as substituent on the aromatic ring a halogen atom, a hydroxyl radical or an alkyl or alkoxy radical, each containing from 1 to 5 carbon atoms, a 2-indolylmethyl radical, a 4-imidazolylmethyl radical, or an alkoxycarbonylmethyl radical containing from 3 to 11 carbon atoms, … - each of R2 and R3, which are identical or different, denotes a linear or branched alkyl radical containing from 1 to 6 carbon atoms, … - n is equal to 1 or 2, … - R4 denotes a hydrogen atom, a formyl radical or a methyl radical, provided, however, that R4 is never a methyl radical when n is equal to 2, and … - either R5 and R6 together form a double bond or R5 denotes a hydrogen atom and R6 a hydroxyl radical, … in the form of mixture of pure diastereoisomers or isomers, their Nb'-oxides and their salts of addition to a pharmaceutically acceptable inorganic or organic acid. …<??>These compounds are antitumour agents. |
