COMPOUND AND METHOD FOR TREATING SKIN FOR ACNE OR PSORIASIS

摘要

The effects of acne and psoriasis are relieved by applying either topically or by oral administration, a compound having structure(I), wherein R1, R2, R3, R4, and R5 are independently selected from the group consisting of H, Cl, straight or branched alkyl of 1 to 10 carbon atoms, NO2, COOR6, CN, OR6, NR6R7, NR6C(=S)NR7R8, NR6COR7, SO2NR6R7, CH(CH3)COOH, CONR6R7, COR6, OCONR6R7, NR6COONR7, R9OR6, NR6SO2R7, Si(CH3)3, and NR6CONR7R8, R3 together with R4 forms a benzo ring or taken together with R2 forms a benzo or tetrahydrobenzo ring or together with R2 and R1 forms a (a) moiety or together with R2 forms a (b) moiety or R2 together with R1 forms a benzo ring or R2 together with R3 forms a (c) or (d) or (e) or (f) moiety, or R1 is independently selected from the group consisting of (g), (h) moiety, R6, R7 and R8 are independently selected from the group consisting of straight or branched alkyl containing from 1 to 10 carbon atoms, aryl containing from 6 to 10 carbon atoms and hydrogen, and R9 is alkylene of 1 to 6 carbon atoms, and iron carbonyl complexes thereof, to an area of the human skin in an amount effective to repair damage due to acne or psoriasis. This treatment is not accompanied by substantial discomfort or dermatological irritation.