| 摘要 |
<p>This invention relates to indole derivatives of general formula (1) and salts thereof, a method for preparing same, and applications thereof in the prevention and treatment of nephritis, wherein R represents hydrogen, cyano or one of various other substituents, l is an integer of 1 or 2, R<1> represents hydrogen, one of various substituents or a group of formula (2) (wherein A represents a single bond, -CH(OH)-, -CH=, -C(=O)- or alkyl, and R<2>, R<3>, R<4>, R<5> and R<6> each represents one of various substituents), and Z represents hydrogen or a group of formula (2) provided that R<1> represents a group of formula (2) when Z represents hydrogen.</p> |
| 申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
TONE, HITOSHI SHINNO MANSION 311;SATO, SEIJI HAITSU DATEMUSUME A402;SATO, HIDEAKI 463-10, KAGASUNO;TAMURA, KATSUMI 1-126, AZA NIBU SHINKIRAI;TAMADA, SHIGEHARU 1-16, AZA NIBU;KONDO, KAZUMI MEZON YAMATO 801 19-27, AZA;KAWAGUCHI, TOMOYUKI KOPO ENZELU 407;NAKANO, YOSHIMASA 37-2, AZA HIGASHINO KASAGI;MURAKAMI, MASAHIRO 207-403, KAGIYACHO;ITO, YOSHIHIKO KITAYAMASUKAIHAITSU 301;KITA, YASUYUKI 2-8, KAMIICHI 3-CHOME;AKAI, SHUJI 2055, HIYOSHIDAI YONBANCHO;FUJIOKA, HIROMICHI 5-22, NYOIDANI 4-CHOME;TAMURA, YASUMITSU 9-24, SAKASEGAWA 2-CHOME;MATOBA, KATSUHIDE 12-7, TERAHATA 2-CHOME;TANIGUCHI, YOUICHI 33, KAMI BEKKU HIGASHI;NISHITANI, SHINJI 211-1, AZA MATSUSHIMA;HAYAKAWA, SATOSHI 25-206, KASUMICHO 3-BAN;KANEYASU, TOSHINORI 34-5, AZA HIGASHIHAMA |
