发明名称 N-SUBSTITUTED-AMIDE-AMINO ACID
摘要 Compounds of the formula <IMAGE> wherein R and R9 are independently hydroxy or lower alkoxy, R1 and R2 are hydrogen or lower alkyl, aryl-lower alkyl having from 7 to 12 carbon atoms, or heterocyclic-lower alkyl having from 6 to 12 carbon atoms, R3, R4, R5, R7 and R8 are hygrogen or lower alkyl, R6 is cycloalkly having from 3 to 20 carbon atoms, aryl or aryl-lower alkyl, and the aryl group contains from 6 to 10 carbon atoms, and their pharmaceutically acceptable, nontoxic acid addition salts and where R or R9 or both are hydroxy, their pharmaceutically acceptable, nontoxic basic salts possess antihypertensive activity.
申请公布号 JPS57176941(A) 申请公布日期 1982.10.30
申请号 JP19820050266 申请日期 1982.03.30
申请人 YUU ESU BUI PHARM CORP 发明人 REIMONDO DEI YOZEFUI;JIERII DABURIYUU SUKIRESU;JIYON TEI SUU;HOWAADO JIYOONZU
分类号 C07D209/20;A61K38/00;A61K38/55;C07C67/00;C07C231/00;C07C231/02;C07C231/12;C07C239/00;C07C271/22;C07C279/18;C07C313/00;C07C323/58;C07C323/60;C07K1/113;C07K5/02;C07K5/06;C07K14/81 主分类号 C07D209/20
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