2-(4-PYRIDYLAMINOMETYL)-BENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY

摘要

Provided herein is 2-(4-pyridylaminomethyl)benzimida-zole derivatives of the following general formula: and 75 novel benzimidazole derivatives are exemplified with a melting point and some of their preparing processes are described. The potent in vitro and in vivo antipicornavirus activities of the compounds of this invention are demonstrated. Some of the compounds of this invention is expected for preventing and treating picornavirus disease.