发明名称 Indenoindole compounds.
摘要 <p>Compounds of the formula &lt;CHEM&gt; wherein R is hydrogen or a lower alkyl group or COR&lt;1&gt;&lt;5&gt; R&lt;1&gt;, R&lt;2&gt;, R&lt;1&gt;&lt;1&gt; and R&lt;1&gt;&lt;2&gt;, are hydrogen or a lower alkyl group, R&lt;3&gt;, R&lt;4&gt;, R&lt;5&gt; and R&lt;6&gt; are hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group or a mono- or di-lower alkyl amino group, NH2 or NR&lt;1&gt;&lt;3&gt;COR&lt;1&gt;&lt;4&gt;, R&lt;7&gt;, R&lt;8&gt;, R&lt;9&gt; and R&lt;1&gt;&lt;0&gt; are hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, or NH&lt;1&gt;&lt;3&gt;COR&lt;1&gt;&lt;4&gt; wherein R&lt;1&gt;&lt;3&gt;, R&lt;1&gt;&lt;4&gt; and R&lt;1&gt;&lt;5&gt; are hydrogen or a lower alkyl group, enantiomers and salts thereof, with the proviso that when R is COR&lt;1&gt;&lt;5&gt; then at least one of R&lt;3&gt; to R&lt;1&gt;&lt;0&gt; are hydroxy or a mono or di-lower alkylamino group, are useful as antioxidants, within the medical and non-medical field. Many of the compounds of formula IA and IB are new and various methods for preparing them are described.</p>
申请公布号 EP0409410(A1) 申请公布日期 1991.01.23
申请号 EP19900306718 申请日期 1990.06.20
申请人 UNIVERSITY OF BATH;UNIVERSITY OF CINCINNATI 发明人 SAINSBURY, MALCOLM;SHERTZER, HOWARD G.
分类号 A61K31/40;A61K31/403;A61K31/404;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P37/00;A61P37/08;A61P39/06;A61P43/00;C07C7/20;C07D209/70;C07D209/94 主分类号 A61K31/40
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