Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked.

摘要

A rapid-releasing oral particle phamaceutical preparation with its unpleasant taste masked comprising a core and a film layer coating the core, the core at least containing a drug having an unpleasant taste and a water-swelling agent, and the film layer at least containing ethylcellulose and a water-soluble substance, the amount of the drug in the core being at most 40 % (based on the final particle preparation and so on), the amount of the water-swelling agent being about 35 % to about 70 %, the amount of ethylcellulose in the film layer being about 3 to about 11 %, and the the amount of the water-soluble substance being about 0.1 to about 0.8 times the weight of the ethylcellulose.