发明名称 Compositions and method for treatment of mast cell-mediated dermatologic disorders using nalmefene.
摘要 <p>A method of treating human or animal patients suffering from mast cell-mediated dermatological disorders comprising the administration to the affected skin areas of a topical composition comprising from about 0.01 to about 10% by weight of the narcotic antagonist nalmefene or one of its salts or esters in a pharmaceutically inert topical vehicle. Compositions suitable for use in such methods include solutions, aerosols, creams, gels, ointments and lotions. The compositions may be applied to the affected areas from 1 to about 6 times daily.</p>
申请公布号 EP0409392(A2) 申请公布日期 1991.01.23
申请号 EP19900305908 申请日期 1990.05.31
申请人 BAKER CUMMINS DERMATOLOGICALS, INC. 发明人 FROST, PHILLIP
分类号 C07D489/08;A61K31/435;A61K31/485;A61P17/00;A61P43/00 主分类号 C07D489/08
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