发明名称 |
DERIVATIVES OF 3,18-DIHYDROXY-9,13-EPOXYLABDANE, METHOD OF OBTAINING THEM AND A HEMOSTATIC PHARMACEUTICAL PREPARATION BASED THEREON. |
摘要 |
<p>New compositions which are derivatives of 3,18-dihydroxy-9,13-epoxylabdane of general formula (I), where R = (a); (b). A method of obtaining said derivatives of 3,18-dihydroxy-9,13-epoxylabdane consists in subjecting the 3,18-dihydroxy-9,13-epoxylabdane to the dehydration in the medium of an organic solvent at the latter's boiling temperatures in the presence of a catalyst and in subsequently extracting the desired product. The proposed compositions have hemostatic properties. A hemostatic pharmaceutical preparation comprises, as an active component, the trihydrate of the sodium salt of 3,16,18-trihydroxy-9,13-epoxylabdane-15-acid.</p> |
申请公布号 |
EP0408749(A1) |
申请公布日期 |
1991.01.23 |
申请号 |
EP19890903944 |
申请日期 |
1988.11.30 |
申请人 |
TASHKENTSKY GOSUDARSTVENNY UNIVERSITET IMENI V.I. LENINA;INSTITUT BIOORGANICHESKOI KHIMII AKADEMII NAUK UZBEXKOI SSR |
发明人 |
ZAINUTDINOV, UMARDZHAN NASRUTDINOVICH;NURMATOVA, MUBARAK P. UL. KHADZHAEVA, PROEZD 1-6;ASLANOV, KHAKIM;SADYKOV, ABID;ABDURAKHMANOV, TAIR;NASIROV, SANZHAR KHAIDAROVICH;ISLAMOV, RAKHIM;DANILCHUK, DMITRY NIKOLAEVICH;YANKOVSKY, BORIS ANDREEVICH;ZAKHAROV, VADIM PAVLOVICH |
分类号 |
A61K9/08;A61K31/19;A61K31/34;A61K31/35;A61K31/365;A61P7/04;C07D307/12;C07D307/94;C07D311/92;C07D311/96;C07D493/10 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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