发明名称 DERIVATIVES OF 3,18-DIHYDROXY-9,13-EPOXYLABDANE, METHOD OF OBTAINING THEM AND A HEMOSTATIC PHARMACEUTICAL PREPARATION BASED THEREON.
摘要 <p>New compositions which are derivatives of 3,18-dihydroxy-9,13-epoxylabdane of general formula (I), where R = (a); (b). A method of obtaining said derivatives of 3,18-dihydroxy-9,13-epoxylabdane consists in subjecting the 3,18-dihydroxy-9,13-epoxylabdane to the dehydration in the medium of an organic solvent at the latter's boiling temperatures in the presence of a catalyst and in subsequently extracting the desired product. The proposed compositions have hemostatic properties. A hemostatic pharmaceutical preparation comprises, as an active component, the trihydrate of the sodium salt of 3,16,18-trihydroxy-9,13-epoxylabdane-15-acid.</p>
申请公布号 EP0408749(A1) 申请公布日期 1991.01.23
申请号 EP19890903944 申请日期 1988.11.30
申请人 TASHKENTSKY GOSUDARSTVENNY UNIVERSITET IMENI V.I. LENINA;INSTITUT BIOORGANICHESKOI KHIMII AKADEMII NAUK UZBEXKOI SSR 发明人 ZAINUTDINOV, UMARDZHAN NASRUTDINOVICH;NURMATOVA, MUBARAK P. UL. KHADZHAEVA, PROEZD 1-6;ASLANOV, KHAKIM;SADYKOV, ABID;ABDURAKHMANOV, TAIR;NASIROV, SANZHAR KHAIDAROVICH;ISLAMOV, RAKHIM;DANILCHUK, DMITRY NIKOLAEVICH;YANKOVSKY, BORIS ANDREEVICH;ZAKHAROV, VADIM PAVLOVICH
分类号 A61K9/08;A61K31/19;A61K31/34;A61K31/35;A61K31/365;A61P7/04;C07D307/12;C07D307/94;C07D311/92;C07D311/96;C07D493/10 主分类号 A61K9/08
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