摘要 |
<p>Furan derivs. of a wide variety of cpds. including steroids prepd. by the reduction of alpha,beta-unsaturated lactones by aluminium derivs. MnAlRmH(n+3)-m where M is an alkali metal, R is lower alkyl or alkoxy group n = 0 or 1 m = 0-3 when n=0 or 0-4 when n=1 Steroidal furans where Q = CH3, CH2OH, CH2OAc, CHO, X = alpha-CHOH, beta-CHOH, alpha-CHOAc, beta-CHOAc, alpha-glucosyloxymethylene contng. up to 4 sugar units, C=O, Y, Y' = H or OH Z = CH2, alpha-CHOH, beta-CHOH, alpha-CHOAc, beta-CHOAc in alpha- or beta-configuration X may be C=O with DELTA4 but not DELTA5 unsaturation. Medicinal cpds. e.g. dietetic aids to nourishment, androgenic/anabolci agents; derivs. with sedative, analgesic, antitussive, properties.</p> |