BUTANE COMPOUNDS OR SALTS THEREOF AND THEIR MEDICAL USES

摘要

The invention relates to butane compounds represented by general formula (I), [wherein R<1> represents hydrogen, halogen, lower alkyl, lower alkoxy or -NHCO(CH2)mCOOR<4> (wherein R<4> represents hydrogen, lower alkyl or aralkyl, and m represents 0 or 1), R<2> represents hydrogen, lower alkyl or aralkyl, R<3> represents hydrogen, lower alkyl, phenyl, substituted phenyl, aralkyl or substituted aralkyl, Het represents pyridyl, substituted pyridyl, N-substituted pyridinium, dioxopyrimidinyl, benzimidazolyl, substituted benzimidazolyl or quinolyl, a, b, c and d each represents hydrogen, or a and b or c and d are bound to each other to form a single bond, and n represents 0 or 1] or salts thereof and their medical uses.