KERATINOCYTE AUTOCRINE FACTOR

摘要

Keratinocyte autocrine factor (KAF) can be isolated from human keratinocytes and is an effective and selective mitogen for keratinocytes in comparison to fibroblasts. Methods of purifying KAF using sulfated glycosaminoglycans, methods to inhibit the effect of KAF using sulfated glycosaminoglycans, and methods to assay for stimulators and inhibitors of KAF activity and production are described.