发明名称 BIS-ACYLOXYMETHYL DERIVATIVES
摘要 This invention relates to new pyridyl, quinoline and acridine bis-acyloxymethyl compounds; to compositions comprising these compounds; and to processes for their utility as fungicides, bactericides and as inhibitors of the growth of cancer in warm-blooded animals. In accordance with this invention, new bis-acyloxymethyl derivatives are provided of formula (I), wherein A is hydrogen, or, A and B are independently selected from substituted and unsubstituted alkyl, cycloalkyl, aryl, alkenyl, cycloalkenyl and alkynyl, or, A and B together comprise a pyrrolizine; L is selected from (II); (III); (IV); and, (V), wherein Y is selected from hydrogen or (VI); each R and Z is independently selected from hydrogen or substituted and unsubstituted alkyl, cycloalkyl, aryl, alkenyl, cycloalkenyl, alkynyl, amine, carboxylic acid group, carboxylic acid ester group, carboxylic acid amide group, sulfonic acid group and sulfonic acid amide group; each Z' is independently selected from hydrogen and substituted or unsubstituted alkyl; M is Z or is selected from halogen, nitro, hydroxyl and substituted or unsubstituted, nitrile, ether, thioether, acylated hydroxyl, sulfonylamide, sulfonylurea, sulfoxide, sulfone and mixtures thereof; each n is the same and is 0 or 1; q is from 0 to 4; and, X is the anion of an acid.
申请公布号 WO9100093(A1) 申请公布日期 1991.01.10
申请号 WO1990US03576 申请日期 1990.06.22
申请人 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW 发明人 ANDERSON, WAYNE, K.;DEAN, DENNIS, C.
分类号 A61K31/44;A61P31/04;A61P35/00;C07D401/04;C07D403/04;C07D487/04 主分类号 A61K31/44
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