Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same.

摘要

A piperidine derivative represented by the following general formula (I): <CHEM> wherein R represents a hydrogen atom or a lower alkyl group; X represent -CH=CH-, -CH2CH2-, or -CH2O-; Y represent an alkylene group having 1 to 5 carbon atoms which may be optionally substituted with a lower alkyl group, or Y represents an -A-O-B- group wherein A and B are the same or different and each independently represents and alkylene group having 1 to 3 carbon atoms which may be optionally substituted with a lower alkyl group is disclosed. Also disclosed are a pharmacologically acceptable salt of a compound of formula (I), a method for preparation of a compound of formula (I), an antihistaminic and antiallergic agent comprising a compound of formula (I), and a method for the treatment of an allergic disease by administering a compound of formula (I).