Benzazine compounds and pharmaceutical uses thereof.

摘要

A benzazine compound, a geometrical isomer of said benzazine compound, an optical isomer of said benzazine compound, and a pharmaceutically acceptable salt of said benzazine compound, said benzazine compound being represented by formula (I): <CHEM> wherein R9 represents <CHEM> X represents oxygen or sulfur; Y represents oxygen or N-R10. Said benzazine compounds exhibit 5-HT3 receptor antagonistic activity, and 5-HT1A receptor and/or dopamine D2 receptor blocking activity so that they are useful as drugs for the prophylaxis or treatment of various digestive diseases vomiting and disturbances in central nervous systems and the like. The intermediates for said benzazine compounds are also disclosed.