| 摘要 |
A method for the manufacture of dimethyl octyl (or pentyl) para-amino benzoic acid is described. The method consists in the carbonylation of para-bromo-dimethyl aniline, in the absence of any promoter, in a reaction system having a pH of above 8 in the presence of an alcohol selected from octanol, pentanol or isomers thereof using a palladium catalyst on an inert support. The reaction is carried out at a temperature in the range of 140 DEG to 200 DEG C. and a pressure of between 1 to 5 atmospheres. The product obtained is characterized by its high purity being substantially free of any impurities.
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