发明名称 |
ANTIHYPERTENSIVE PREPARATION CONTAINING A MIXTURE |
摘要 |
<p>Compositions for treating hypertension comprising an effective amount of a dihydropyridine of the formula <IMAGE> in which X is 1 or 2 identical or different substituents from the group consisting of nitro, chlorine and trifluoromethyl, or together with the phenyl ring, the group <IMAGE> R1 is alkyl of 1 to 4 C atoms, which is optionally substituted by alkoxy of 1 to 4 C atoms, R2 is alkyl of 1 to 12 C atoms, which is optionally substituted by alkoxy of 1 to 3 C atoms, fluorine or N-methyl-N-benzylamino and R3 is alkyl of 1 to 4 C atoms, cyano or hydroxymethyl, and a pyridazodiazepine of the formula <IMAGE> in which R4 is aralkyl, R5 is hydrogen or alkyl of 1 to 8 C atoms, R6 is hydrogen or alkyl of 1 to 8 C atoms and R7 and R8 are hydrogen, or together, an oxo group, are described.</p> |
申请公布号 |
GR3000188(T3) |
申请公布日期 |
1990.12.31 |
申请号 |
GR19890400205T |
申请日期 |
1989.10.20 |
申请人 |
BAYER AG;F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT |
发明人 |
GARTHOFF, BERNWARD, DR.;KAZDA, STANISLAV, DR.;KNORR, ANDREAS, DR.;GEROLD, MARCEL, DR.;HEFTI, FRIDOLIN, DR. |
分类号 |
A61K31/50;A61K31/55;A61P9/12;(IPC1-7):A61K31/55 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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