摘要 |
<p>The invention relates to a process for the preparation of guanidine-derivatives of general formula (I), wherein R means a C1-4 alkyl group, M means a hydrogenatom, sodium-, potassium-, or calcium ion, A means an -S-, -SO-, or -SO2-group; in a way, that thiocarbamide derivatives of general formula (II) are oxidized optionally in the presence of an inorganic or organic solvent and the sulfonic acid derivative of general formula (III) obtained is reacted with an aniline derivative of general formula (IV) optionally in the presence of an inorganic or organic solvent.</p> |