| 摘要 |
<p>A process for the preparation of submicron size, monodisperse drug-particles of a drug of low water-solubility by emulsifying an organic solution of the drug in an aqueous phase and then removing the organic solvent resulting in drug precipitation, containing the steps: a) emulsifying the organic solution in the presence of an emulsifier comprising a surfactant capable of adsorption on the surface of a precipitated drug-particle; b) removing the organic solvent from the suspension; and c) recovering the precipitated drug-particles from the aqueous phase or storing the same in the original aqueous phase.</p> |
