ANTICANCER DRUG AND NOVEL HETEROCYCLIC COMPOUND USEFUL AS ANTICANCER DRUG OR ITS SALT

摘要

NEW MATERIAL:A heterocyclic compound expressed by the formula or salt of said compound (R1 is H, lower alkyl or styryl may be substituted of m- or p-position by hydroxyl group, lower alkoxy or halogen; R2 is H, hydroxyl group, lower alkoxy or acyl; R3 is H, hydroxyl group, lower alkoxy or acyl; R4 is H, or lower alkyl; X is O or S; Y is O or N which may be substituted by lower alkyl group). EXAMPLE:3-hydroxy-6-methyl-5-methoxy-2-pentyl-4H-pyran-4-on. USE:Useful as anticancer drug. Applicable not only as treating agent of cancer but also preventive of cancer and further useful as a novel bioactive substance. PREPARATION:Said compound is a stress compound in the case of injuring Allium sativum Linne called as garlic belonging to Liliaceae and extracted and separated at 1 day - several month after the injury.