Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface.

摘要

A thermoplastic polyurethaneurea having free amino groups and comprising a product from the reaction of a diisocyanate, a polyamine and a misture of polyols comprising a fluorinated polyol and a non-fluorinated polyol selected from polyalkyleneoxide polyols and polyester polyols. A medical device having a hemocompatible surface comprising a shaped polymeric article having thereon a coating of a thermoplastic polyurethaneurea as claimed in Claim 1, and an antithrombogenic agent covalently affixed to amino groups of the polyurethaneurea coating.