| 发明名称 |
MODIFIED VP1/P2A REGION OF THE RHINOVIRUS SYSTEM |
| 摘要 |
The present invention relates to systems which make it possible to introduce mutations in the VPl/2A and in the overall coding region of the protease 2A, test systems by means of which the "cis" and "trans" activity can be investigated, oligonucleotides which code the mutations, as well as the oligopeptides derived therefrom and their use. It further relates to oligopeptides which are cleaved by protease 2A in trans with varying degrees of efficiency, and the use thereof.
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| 申请公布号 |
CA2019661(A1) |
申请公布日期 |
1990.12.25 |
| 申请号 |
CA19902019661 |
申请日期 |
1990.06.22 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL G.M.B.H. |
发明人 |
SOMMERGRUBER, WOLFGANG;VOLKMANN, PETER;FESSL, FRIEDERIKE;MAURER-FOGY, INGRID;KUECHLER, ERNST;BLAAS, DIETER;SKERN, TIMOTHY;ZORN, MANFRED;AUER, HERBERT |
| 分类号 |
C12N15/09;A61K31/70;A61K38/00;A61K38/55;A61K39/00;A61K39/395;A61P31/12;C07K7/00;C07K7/06;C07K7/08;C07K14/00;C07K14/095;C07K14/81;C07K16/08;C07K16/10;C07K16/40;C12N;C12N9/50;C12N15/41;C12N15/47;C12N15/57;C12N15/62;C12Q1/70;(IPC1-7):C12N15/41;C07H21/00;C12Q1/68 |
主分类号 |
C12N15/09 |
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