摘要 |
All-trans or 13-cis retinoic acid-based aqueous gel. This gel is characterized in that retinoic acid is present, in a soluble and stable state, in a proportion by weight of 0.025 to 0.2 % by weight, in the presence of 0.2 to 1.8 % by weight of beta -cyclodextrine and a hydroxylated organic base in a proportion such that the pH of said gel is of between about 7.0 and 8.5, the gelling agent being present in a proportion such that the gel has a viscosity of between about 1.5 Pa.s. and 10 Pa.s. This gel can be used in the pharmaceutical and cosmetic fields, particularly in the treatment of various forms of acne, psoriasis or other dermatological ailments. |