发明名称 GLUTAMIC ACID DERIVATIVES
摘要 The present invention relates to compounds of formula (I): <CHEM> wherein Y is sulphur or oxygen; R<2> and R<3> are the same or different and are hydrogen or C1-4 alkyl; R<4> is NR<1><1>R<1><2>; R<1><1>, R<1><2>, R<5> and R<6> are the same or different and are hydrogen, C1-4 alkyl or C1-12 acyl; R<7>, R<8>, R<9> and R<1><0> are the same or different and are hydrogen, halo, C1-4 haloalkyl, C1-4 alkyl and C1-4 alkoxy; and n is 2, 3, 4 or 5; m is 0 or an integer from 1 to 5; or a salt thereof, methods for the preparation of the compounds of the formula (I), pharmaceutical formulations containing them, and their use in the treatment of neoplastic growth.
申请公布号 AU5646090(A) 申请公布日期 1990.12.18
申请号 AU19900056460 申请日期 1990.05.16
申请人 THE WELLCOME FOUNDATION LIMITED 发明人 ERIC CLEVELAND BIGHAM;STEPHEN JOSEPH HODSON
分类号 A61K31/505;A61P35/00;C07D239/48 主分类号 A61K31/505
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