发明名称 |
CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS |
摘要 |
Peptides immunoreactive with antibodies to native proteins, and which have at least two cysteine residues that contribute to mimicking an epitope of the protein, are prepared with the cysteine thiol groups protected. When deprotected, the peptides have enhanced immunoreactivity. The peptides are particularly useful for detecting antibodies or antigens associated with retroviruses, including the clinically important lymphotropic retroviruses HIV-1, HIV-2, HTLV-I, and HTLV-II. |
申请公布号 |
WO9015071(A1) |
申请公布日期 |
1990.12.13 |
申请号 |
WO1990US03148 |
申请日期 |
1990.06.04 |
申请人 |
GENETIC SYSTEMS CORPORATION |
发明人 |
BLAKE, JAMES;COLE, CAROL-ANN;COLEMAN, PATRICK;MONJI, NOBUO;MONTANA, JOHN, P. |
分类号 |
C07K7/06;C07K1/107;C07K1/113;C07K7/08;C07K14/00;C07K14/15;C07K14/155;C07K14/16;C07K14/705;C07K17/02;C07K17/08;C07K17/12;C07K17/14;C07K19/00;G01N33/543;G01N33/569;G01N33/574 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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