发明名称 MONOCLONAL ANTIBODY SPECIFIC THROMBIN INHIBITOR
摘要 <p>The invention concerns a process for the preparation of hybridoma cells which secrete monoclonal antibodies specific for hirudin, the hybridoma cells themselves, the monoclonal antibodies specific for hirudin secreted by these hybridoma cells, derivatives thereof, and a process for the preparation of said antibodies and derivatives. These monoclonal anti-hirudin antibodies and their derivatives are useful for the determination of hirudin and as an antidote to hirudin. The invention also concerns test kits and pharmaceutical compositions comprising said monoclonal antibodies and/or derivatives.</p>
申请公布号 JPH02299583(A) 申请公布日期 1990.12.11
申请号 JP19900013756 申请日期 1990.01.25
申请人 CIBA GEIGY AG 发明人 JIYANNMARUKU SHIERAETSUPI;DEIITOMAA GEE BURAUN
分类号 G01N33/577;A61K31/00;A61K38/00;A61K39/395;A61P7/00;A61P7/02;C07K16/38;C12N5/10;C12N5/20;C12N15/02;C12P21/08;C12R1/91 主分类号 G01N33/577
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