发明名称 TUMOR THERAPEUTIC AGENT AND A PROCESS FOR ITS PREPARATION
摘要 A process for the preparation of a therapeutic agent from tumor cells for the therapy of tumorous diseases is described. This entails either human tumor cells which carry antigens which are bound by the monoclonal antibodies which recognize an antigen (Ag1) having a molecular weight of approximately 33 KD + 3, or an antigen (Ag2) having a molecular weight of approximately 134 KD + 3, or an antigen (Ag3) having a molecular weight of approximately 80 KD + 3, or an antigen (Ag4) having a molecular weight of approximately 55 KD + 3, or an antigen (Ag5) having a molecular weight of approximately 60 KD + 3, or an antigen (Ag6) having a molecular weight of approximately 54 KD + 3, or an antigen (Ag7) having a molecular weight of approximately 260 KD + 3, or an antigen (Ag8) having a non-determinable molecular weight, or an antigen (Ag9) having a non-determinable molecular weight, or an antigen (Ag10) having a molecular weight of approximately 143 KD + 3 and 119 KD + 3, or an antigen (Ag11) having a molecular weight of approximately 178 KD + 3, or an antigen (Ag12) having a non-determinable molecular weight, or an antigen (Ag13) having a molecular weight of approximately 34 KD + 3, or an antigen (Ag14) having a molecular weight of approximately 195 KD + 3, or an antigen (Ag15) having a molecular weight of approximately 44 KD + 7, or an antigen (Ag16) having a molecular weight of approximately 43 KD + 3, or an antigen (Ag17) having a molecular weight of approximately 130 KD + 3, being dried or stabilized by chemical treatment, or antigens being isolated from human tumor cells using these monoclonal antibodies, and being processed to a therapeutic agent, neuraminidase being added where appropriate.
申请公布号 CA1277600(C) 申请公布日期 1990.12.11
申请号 CA19850490026 申请日期 1985.09.05
申请人 BEHRINGWERKE AKTIENGESELLSCHAFT 发明人 BOSSLET, KLAUS;SEDLACEK, HANS-HARALD
分类号 A61K35/12;A61K38/47;A61K39/00 主分类号 A61K35/12
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