| 摘要 |
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thromhosis. wherein X represents a group of the formula: in which Y is a group of the formula: -(CH2)m-, m being an integer of 2 or 3, or or a group of the formula: -OR in which R is a hydrogen atom or a lower alkyl group, and n represents an lnteger of 1 to 5. |
| 申请人 |
EISAI CO., LTD. |
发明人 |
SOUDA, SHIGERU;SHIMOMURA, NAOYUKI;UEDA, NORIHIRO;MIYAZAWA, SHUHEI;YAMANAKA, TAKASHI;MIYAMOTO, KANAME;HISHINUMA, IEHARU;NAGAKAWA, JUNICHI;NAGAOKA, NAOKO;KAWASHIMA, HIDETOSHI;KAWATA, TSUTOMU;NAGAOKA, JUNSAKU;WAKABAYASHI, TSUNEO |
