| 摘要 |
The invention relates to new 4-hydroxyindole derivatives of general formula: <IMAGE> in which R represents a labile protective group and R1 can represent hydrogen, a C1-C6 alkyl radical, a C3-C6 cycloalkyl radical, a lower alkoxy radical, a lower hydroxyalkyl radical, a lower (lower alkoxy) alkyl radical, a phenyl radical optionally substituted with a halogen atom or a lower alkyl or lower alkoxy radical, a cyano radical, a radical of formula <IMAGE> in which R2 and R3, which may be identical or different, each represent hydrogen or a lower alkyl radical, R4 represents a hydroxy group, a lower alkyl or lower alkoxy radical or a radical <IMAGE> in which R2 and R3 have the same meaning as above, R5 represents a lower alkyl radical and Alk represents a single bond or a straight- or branched-chain alkylene radical having from 1 to 4 carbon atoms. The invention also relates to a process for preparing 4-(3-amino-2-hydroxypropoxy)indole derivatives from the said 4-hydroxyindole derivatives.
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