SHORT THERAPEUTIC dsRNA OF DEFINED STRUCTURE

摘要

The present invention relates to the induction of proteins and the activation of enzymes in the cells of living organisms, including human beings. According to the invention, long nucleic and complexes, such as the polyriboinosinate and polycytidylate complexes, are modified to yield short dsRNA of defined sequence. Said short dsRNAs of defined sequence retain the ability to induce proteins and activate enzymes but are not as toxic as long dsRNA.