发明名称 5,11-DIHYDRODIBENZO (B,E)(1,4)-THIAZEPINES
摘要 The invention provides compounds of the formula:- <CHEM> wherein k is 1, 2 or 3; m is 1, 2 or 3; n is 1, 2 or 3; p is 0, 1 or 2; X is O, S or a direct link, with the proviso that when X is O or S, n is 2 or 3; R<1> is H or C1-C4 alkyl; and R<2> is an optionally substituted phenyl or heteroaryl group; and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of motility disorders, particularly those of the gut such as irritable bowel syndrome.
申请公布号 AU5595490(A) 申请公布日期 1990.11.29
申请号 AU19900055954 申请日期 1990.05.25
申请人 PFIZER INC. 发明人 DAVID ALKER;PETER EDWARD CROSS;ROBERT JOHN BASS
分类号 A61K31/55;C07D;C07D207/09;C07D417/06;C07D417/14 主分类号 A61K31/55
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