摘要 |
<p>The present invention relates to compounds of formula (I), wherein Y is sulphur or oxygen; R?2 and R3¿ are the same or different and are hydrogen or C¿1-4? alkyl; R?4 is NR11R12; R11, R12, R5 and R6¿ are the same or different and are hydrogen, C¿1-4? alkyl or C1-12 acyl; R?7, R8, R9 and R10¿ are the same of different and are hydrogen, halo, C¿1-4? haloalkyl, C1-4 alkyl and C1-4 alkoxy; and n is 2, 3, 4 or 5; m is 0 or an integer from 1 to 5; or a salt thereof, methods for the preparation of the compounds of formula (I), pharmaceutical formulations containing them, and their use in the treatment of neoplastic growth.</p> |