发明名称 |
LABELED CHEMOTATIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION |
摘要 |
Chemotactic peptides are disclosed which comprise a peptide having the general formula: N - X - Y - Leu - Phe - Z - W wherein: X is a bulky group; Y is Met or Nle; Z is a bond or a spacer sequence; and W is a detectable label or a substituent for attaching a label or for attachment to a carrier. Compositions containing these chemotactic peptides are also disclosed. These compositions are useful for instance in the form of pharmaceutical compositions for treating a localized site of infection or inflammation in an individual. |
申请公布号 |
AU5659090(A) |
申请公布日期 |
1990.11.29 |
申请号 |
AU19900056590 |
申请日期 |
1990.05.09 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
ALAN JAY FISCHMAN;ROBERT HAROLD RUBIN;HARRY WILLIAM STRAUSS;ANTHONY JOSEPH FUCCELLO;DANIEL JOHN KROON;DOUGLAS JAMES RIEXINGER |
分类号 |
A61K38/00;A61K9/08;A61K38/08;A61K49/00;A61K51/00;A61K51/08;A61P29/00;A61P31/04;C07K5/10;C07K5/103;C07K7/06;G01N33/60;G01N33/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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