发明名称 |
PROCESS FOR PRODUCING NEW 4-/4-/4-/4-//2-(2,4 DIFLUOR-PHENYL)-2-(1H-AZOLYL-METHYL)- -1,3 DIOXOLANE-4-IL/METHOXY/-PHENYL/-1-DERIVATIVES AND PHARMACEUTICAL PREPARATIVES CONTAINING SUCH COMPOUNDS |
摘要 |
4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4 -yl]methoxy]pheny l ]-1-piperazinyl]phenyl]triazolones and imidazolones of formula <CHEM> wherein Q is CH or N; Y is a radical of formula <CHEM> R<1> is C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl; and R<2> is C1-6alkyl, C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl, the acid addition salts and stereoisomeric forms thereof; said compounds having antifungal properties. Pharmaceutical compositions containing such compounds as an active ingredient; methods of preparing said compounds and pharmaceutical compositions. |
申请公布号 |
HU903767(D0) |
申请公布日期 |
1990.11.28 |
申请号 |
HU19900003767 |
申请日期 |
1990.06.08 |
申请人 |
JANSSEN PHARMACEUTICA N.V.,BE |
发明人 |
HEERES,JAN,BE;BACKX,LEU JACOBUS JOZEF,BE |
分类号 |
C07D405/14;A61K31/00;A61K31/41;A61K31/415;A61K31/4166;A61K31/4245;A61K31/495;A61K31/496;A61P31/00;A61P31/04;A61P31/10;C07D521/00 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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