发明名称 Stable solvent adducts of Z-1-(p- beta -dimethylaminoethoxy-phenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene
摘要 This invention relates to new stereochemically pure and stable adducts of Z-1-(p- beta -dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solvents which by virtue of their marked antioestrogenic activities may be used for the therapeutic treatment of benign breast diseases and hormone-dependent mammary tumors, in particularly by percutaneous application.
申请公布号 US4973755(A) 申请公布日期 1990.11.27
申请号 US19880183068 申请日期 1988.04.19
申请人 HEUMANN PHARMA GMBH & CO. 发明人 GRAFE, INGOMAR;SCHICKANEDER, HELMUT;JUNGBLUT, PETER W.;AHRENS, KURT H.
分类号 A61K31/135;A61P35/00;C07C67/00;C07C213/00;C07C213/02;C07C217/16;C07C217/20;(IPC1-7):C07C217/54 主分类号 A61K31/135
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