发明名称 |
Stable solvent adducts of Z-1-(p- beta -dimethylaminoethoxy-phenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene |
摘要 |
This invention relates to new stereochemically pure and stable adducts of Z-1-(p- beta -dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solvents which by virtue of their marked antioestrogenic activities may be used for the therapeutic treatment of benign breast diseases and hormone-dependent mammary tumors, in particularly by percutaneous application.
|
申请公布号 |
US4973755(A) |
申请公布日期 |
1990.11.27 |
申请号 |
US19880183068 |
申请日期 |
1988.04.19 |
申请人 |
HEUMANN PHARMA GMBH & CO. |
发明人 |
GRAFE, INGOMAR;SCHICKANEDER, HELMUT;JUNGBLUT, PETER W.;AHRENS, KURT H. |
分类号 |
A61K31/135;A61P35/00;C07C67/00;C07C213/00;C07C213/02;C07C217/16;C07C217/20;(IPC1-7):C07C217/54 |
主分类号 |
A61K31/135 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|