发明名称 Use of imidazodiazepines in the treatment of neurological symptoms associated with circulatory disorders of the brain.
摘要 The known compounds of the general formula <IMAGE> in which A together with the two carbon atoms identified by alpha and beta represent the group <IMAGE> R<1> is halogen, cyano, lower alkyl, lower 1-alkenyl, lower alkoxymethyl or the group -COOR<6> or -C IDENTICAL C-R<7>, R<2> is hydrogen and R<3> is lower alkyl or R<2> and R<3> together are dimethylene or trimethylene, R<4> and R<5> are each hydrogen, halogen, trifluoromethyl or lower alkyl, R<6> is lower alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-lower alkyl and R<7> is hydrogen, lower alkyl, where the compounds of the formula I have the (S) or (R,S) configuration with respect to the carbon atom identified by Y when R<2> and R<3> together denote dimethylene or trimethylene, can be used for the treatment of neurological symptoms associated with circulatory disorders of the brain.
申请公布号 EP0398171(A2) 申请公布日期 1990.11.22
申请号 EP19900108874 申请日期 1990.05.11
申请人 F. HOFFMANN-LA ROCHE AG 发明人 SCOLLO-LAVIZZARI, GIUSEPPE, PROF.-DR.
分类号 C07D487/04;A61K31/55;A61P25/00;A61P25/28;C07D495/14 主分类号 C07D487/04
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