Human prourokinase variants, methods of producing same, DNA sequences, plasmids and hosts therefor.

摘要

A human prourokinase variant deficient in all or at least part of the first loop region or all or at least part of the third region of the epidermal growth factor (EGF) domain of human prourokinase, which shows a long blood half-life comparable to that of the whole EGF domain-deficient PUK variant.