发明名称 NEW PEPTIDE AND HYPOTENSIVE AGENT
摘要 NEW MATERIAL:Formula I to formula III and salts thereof. USE:A hypotensive agent. The above-mentioned compounds have angiotensin conversion enzyme inhibiting action and vasodepressor action and have extremely high safeness and are usable also as a physiologically functional food in addition to medicine. PREPARATION:Sap of fig tree is preferably subjected to heat treatment in order to block action of protease and then subjected to solid liquid separation. Then treatment of ultrafiltration, gel filtration, etc., is applied to the resultant liquid to remove a high-molecular substance and then the resultant aqueous solution is subjected to separation and purification with a column chromatography and high performance liquid chromatography to provide the aimed material.
申请公布号 JPH02282394(A) 申请公布日期 1990.11.19
申请号 JP19890104265 申请日期 1989.04.24
申请人 AGENCY OF IND SCIENCE & TECHNOL;SHOWA SANGYO CO LTD 发明人 MARUYAMA SUSUMU;TANAKA HIDEOKI;MAEDA HIDEKATSU;MITSUYOSHI SHINSUKE;KANEKO TOSHIYUKI;YOSHIZAWA YASUKO;FUKUI FUMIO
分类号 C12N9/99;A61K36/60;A61K38/00;A61P9/12;C07K5/08;C07K5/083;C07K7/06;C07K14/415 主分类号 C12N9/99
代理机构 代理人
主权项
地址