发明名称 |
SEX-ASSOCIATED MEMBRANE PROTEINS AND METHODS FOR INCREASING THE PROBABILITY THAT OFFSPRING WILL BE OF A DESIRED SEX |
摘要 |
A method of sorting living cells based on DNA content. Mammalian sperm subpopulations enriched in X- or Y-sperm. X- and Y-enriched sperm-plasma-membrane vesicles. Substantially pure sex-associated membrane (SAM) proteins. Antibodies binding to X- or Y-SAM proteins, essentially free of antibodies binding to Y- or X-SAM proteins respectively, or to the H-Y antigen. Semen samples enriched for X- or Y-sperm. Methods for increasing the probability that offspring will be male or female comprising the step of allowing a sperm from an enriched semen sample to fertilize an ovum. Methods for increasing the probability that offspring will be male or female comprising the step of immunizing a female with X- or Y-SAM proteins. Methods of decreasing fertility comprising the step of immunizing a female with both X- and Y-sperm. Methods of increasing the probability that mammalian offspring will carry a gene for a particular sex-chromosome linked trait. |
申请公布号 |
WO9013315(A1) |
申请公布日期 |
1990.11.15 |
申请号 |
WO1989US02069 |
申请日期 |
1989.05.12 |
申请人 |
CYTOGAM, INC. |
发明人 |
SPAULDING, GLENN, F. |
分类号 |
A01K67/02;A61K35/52;A61K38/00;A61K39/00;A61K39/395;A61P13/02;A61P15/00;C07K1/22;C07K14/435;C07K14/47;C07K14/705;C07K16/00;C07K16/18;C07K16/28;C12N5/10;C12N15/02;C12N15/09;C12P21/08;C12R1/91;G01N33/50;G01N33/53 |
主分类号 |
A01K67/02 |
代理机构 |
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代理人 |
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