HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN E. COLI
摘要
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA.
申请公布号
WO9013648(A1)
申请公布日期
1990.11.15
申请号
WO1990US02452
申请日期
1990.05.08
申请人
E.I. DU PONT DE NEMOURS AND COMPANY
发明人
DAVIS, GARY, LEE;KNABB, ROBERT, MADARA;REILLY, THOMAS, MICHAEL;SISK, WILLIAM, PERRY