发明名称 |
TETRAHYDRONAPHTHALENE DERIVATIVES |
摘要 |
It was found that the novel tetrahydronaphthalene derivatives of the formula …<IMAGE>… in which R<1> to R<6> and n have the meaning given in Claim 1,… have a pronounced action against cerebral insufficiency or an action improving cognitive functions and are also able to decrease the multiple resistance to cytostatics in the treatment of tumours or chloroquine resistance in the treatment of malaria. They can therefore be used as medicaments, in particular for the control or prevention of cerebral insufficiency or for the improvement of cognitive functions. The compounds of the formula I can be prepared by O-acylation of a likewise novel compound of the formula …<IMAGE>… |
申请公布号 |
AU5140390(A) |
申请公布日期 |
1990.11.15 |
申请号 |
AU19900051403 |
申请日期 |
1990.03.16 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
URS HENGARTNER;HENRI RAMUZ |
分类号 |
A61K31/215;A61K31/357;A61K31/36;A61P25/28;A61P33/02;A61P35/00;C07C35/52;C07C57/58;C07C57/76;C07C59/48;C07C69/732;C07C215/42;C07C219/24;C07C323/52;C07D317/58;C07D319/18 |
主分类号 |
A61K31/215 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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