4-Imidazoline derivatives and their use in preparing pharmaceutical compositions.

摘要

4-Imidazoline derivatives represented by the formula (I) and/or formula (II): <CHEM> wherein R<1> represents C1-C8 alkyl, C3-C8 alkenyl, C3-C8 alkynyl, C3-C8 cycloalkyl, or optionally substituted aralkyl; R<2> and R<3> independently represent hydrogen, C3-C20 alkyl, C3-C20 alkenyl, C3-C20 alkynyl, C3-C20 alkoxy, C3-C20 alkenyloxy, C3-C20 alkynyloxy, C3-C8 cycloalkyl, C1-C10 alkylthio, or optionally substituted aralkyl or aralkyloxy; R<4> represents C1-C6 alkyl, C3-C8 cycloalkyl, or optionally substituted aralkyl; provided that R<2> and R<3> cannot be hydrogen at the same time, and pharmaceutically acceptable salts thereof. A pharmaceutical formulation containing the compound is also provided.