发明名称 Novel bis-2,4-dioxothiazolidines.
摘要 <p>A compound of formula (I): &lt;CHEM&gt; or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, characterised in that: R&lt;1&gt; represents hydrogen, alkyl, aralkyl or aryl and R&lt;2&gt; represents hydrogen or R&lt;1&gt; and R&lt;2&gt; together represent a bond; R&lt;3&gt; represents hydrogen and R&lt;4&gt; represents hydrogen, alkyl, aralkyl or aryl or R&lt;3&gt; and R&lt;4&gt; together represent a bond; X represents a bond, &gt;C=O, &gt;CHOH, O, S or NR wherein R is an alkyl group; n represents an integer 1, 2 or 3; m represents an integer 1, 2 or 3 and A&lt;1&gt; and A&lt;2&gt; each independently represent a benzene ring having a total up to 5 substituents comprising up to 3 optional substituents; a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such compounds and compositions in medicine.</p>
申请公布号 EP0397453(A1) 申请公布日期 1990.11.14
申请号 EP19900304951 申请日期 1990.05.08
申请人 BEECHAM GROUP P.L.C. 发明人 HINDLEY, RICHARD MARK, BEECHAM PHARMACEUTICALS
分类号 C07D277/20;A61K31/425;A61K31/426;A61P3/06;A61P3/08;A61P9/12;C07D277/34 主分类号 C07D277/20
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