发明名称 An aqueous granulation solution and a method of tablet granulation.
摘要 The invention discloses an aqueous granulating solution containing sodium, potassium or mixed sodium potassium salt of an edible organic acid chosen from the group consisting of citric, malic, tartaric or fumaric acid and optionally containing sodium or potassium bicarbonate. The granulating solution is especially useful for granulating finely divided solids including acetaminophen, ketoprofen or calcium carbonate. The resulting granulate may be used to prepare a swallow tablet or mixed with an edible organic acid and the mixture tableted to provide an effervescent tablet without resorting to controlled reaction or special handling techniques.
申请公布号 EP0396972(A2) 申请公布日期 1990.11.14
申请号 EP19900107972 申请日期 1990.04.26
申请人 BAYER AG 发明人 DAHER, LAWRENCE J.
分类号 A61K9/16;A61K9/20;A61K9/46 主分类号 A61K9/16
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