发明名称 Arylthiazolylimidazoles as 5HT3 Antagonists.
摘要 <p>Arylthiazolylimidazoles as 5HT3 antagonists useful in the treatment of nausea, anxiety, pain, schizophrenia and gastrointestinal disorders, of the formula Ar-HET-CH2-X (I) and their pharmaceutically acceptable acid addition salts, wherein Ar is pyridyl, 3-indolyl, 8-quinolyl, phenyl or mono- or disubstituted phenyl wherein said substituent is each methyl, methoxy, fluoro, chloro or bromo; HET is thiazolyl; and X is imidazole or mono- or dimethylimidazole.</p>
申请公布号 EP0397365(A1) 申请公布日期 1990.11.14
申请号 EP19900304685 申请日期 1990.04.30
申请人 PFIZER INC. 发明人 NAGEL, ARTHUR ADAM;RIZZI, JAMES PATRICK;ROSEN, TERRY JAY
分类号 A61K31/425;A61K31/44;A61K31/47;A61P1/00;A61P1/04;A61P1/08;A61P25/04;A61P25/18;A61P25/20;A61P29/00;A61P43/00;C07D417/06;C07D417/14 主分类号 A61K31/425
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