发明名称 BICYCLO-SUBSTITUTED PHENYLACETONITRILE DERIVATIVES
摘要 The invention relates to compounds of the formula: and the pharmaceutically acceptable salts and hydrates thereof wherein R1 and R2 are the same or different and each is selected from hydrogen,halo, C1-C4 alkyl, C1-C4 alkoxy or trifluoromethyl; R3 is selected from straight or branched chain (a) alkyl of from about 1 to 15 carbon atoms or (b) alkenyl of from about 2 to 15 carbon atoms; R4 is selected from hydrogen or C1-C4 alkyl; R5 is a bicyclic group selected from or wherein R6 and R7 are the same as defined above for R1 and R2; and n is an integer from 2 to 4, inclusive; which are useful as cardiovascular agents.
申请公布号 CA1276178(C) 申请公布日期 1990.11.13
申请号 CA19860520675 申请日期 1986.10.16
申请人 SEARLE (G.D.) & CO. 发明人 LIANG, CHI-DEAN
分类号 A61K31/135;A61K31/275;C07C;C07C255/32;C07C255/33;C07C255/42;C07C255/43;C07C255/58 主分类号 A61K31/135
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