| 摘要 |
PURPOSE:To obtain 1,1,1-trihalogeno-2-nitroethane in high yield, said nitroethane is useful as a synthetic intermediate of unsaturated amines having excellent insecticidal properties by reaction of 1,1-dihalogenoethylene with nitric acid and hydrogen chloride or hydrogen bromide. CONSTITUTION:A compound of formula I (X<1>, X<2> are halogen) is allowed to react with nitric acid or a nitrate salt, and hydrogen chloride or hydrogen bromide or their salt in a tightly sealed system at 0 to 100 deg.C or in an open system at 10 to 35 deg.C to give a compound of containing II (X<3> is C1, Br). The compound of formula II is allowed to react with an amine of formula III (R<1> is H, alkyl which may be halogenated. aralkyl, phenyl; A is 3- or 4-pyridyl, pyrazinyl. phenyl; (n) is 0 to 2) and another amine of formula IV (R<3> is H, alkyl, aralkyl; R<4> is H, alkyl, alkenyl, phenyl, amino) to give an alpha-unsaturated amine of formula V.
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