摘要 |
PURPOSE:To strengthen the film structure and preserve liposome without leakage or agglomeration at the time of preserving to be utilized for a carrier, the drug delivery system or the like by adding gelatin in a preserved liquid of liposome. CONSTITUTION:Leakage agglomeration is controlled to a large extent by adding gelatin in liposome preserved liquid to strengthen the film structure of liposome and preserve a liposome stably. This method is effective for controlling agglomeration of liposome to be formed when liquid is dispersed in the water. As for a liposome film forming lipid, for example, lecithin, phosphatidyl ethanolamine or phosphatidic acid is used. It is better to add a film structure strengthening agent such as sterol for a constituting component of the liposome film. Further, an electric charge donor such as stearic acid can be added therein. The liposome can be utilized for cell separation, a carrier for chemicals or the like. |